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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDHX
All Species:
53.94
Human Site:
S414
Identified Species:
84.76
UniProt:
O00330
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00330
NP_001128496.1
501
54122
S414
P
E
E
Y
Q
G
G
S
F
S
I
S
N
L
G
Chimpanzee
Pan troglodytes
XP_001149489
501
54051
S414
P
E
E
Y
Q
G
G
S
F
S
I
S
N
L
G
Rhesus Macaque
Macaca mulatta
XP_001109997
446
48686
F373
G
M
F
G
I
D
E
F
T
A
V
I
N
P
P
Dog
Lupus familis
XP_533153
501
54075
S414
P
E
E
Y
Q
G
G
S
F
S
I
S
N
L
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BKZ9
501
53981
S414
P
E
E
Y
Q
G
G
S
F
S
I
S
N
L
G
Rat
Rattus norvegicus
P08461
632
67147
T547
P
H
E
F
Q
G
G
T
F
T
I
S
N
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026358
502
53201
S413
P
E
E
Y
Q
G
G
S
F
S
I
S
N
L
G
Frog
Xenopus laevis
NP_001087423
478
50485
S389
P
E
E
Y
Q
G
G
S
F
S
I
S
N
L
G
Zebra Danio
Brachydanio rerio
NP_956854
490
51982
S404
P
E
E
Y
Q
G
G
S
F
S
V
S
N
L
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624025
598
64649
T507
P
E
E
F
Q
G
G
T
F
T
I
S
N
L
G
Nematode Worm
Caenorhab. elegans
Q19749
507
53448
T422
P
H
E
F
Q
G
G
T
F
T
V
S
N
L
G
Sea Urchin
Strong. purpuratus
XP_001177721
482
51019
S401
L
D
E
F
Q
G
G
S
F
S
I
S
N
L
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q0WQF7
637
68844
T549
P
H
E
F
Q
G
G
T
F
S
I
S
N
L
G
Baker's Yeast
Sacchar. cerevisiae
P12695
482
51800
T395
P
E
E
F
Q
G
G
T
I
C
I
S
N
M
G
Red Bread Mold
Neurospora crassa
P20285
458
48601
T385
N
P
A
V
Q
S
F
T
A
I
I
N
P
P
Q
Conservation
Percent
Protein Identity:
100
99.5
87
90.2
N.A.
85.2
34.4
N.A.
N.A.
72.1
58.8
58
N.A.
N.A.
36.4
37.2
47.3
Protein Similarity:
100
99.8
87.6
93.2
N.A.
91.4
49.6
N.A.
N.A.
82
73.4
73
N.A.
N.A.
51.6
56.7
63
P-Site Identity:
100
100
6.6
100
N.A.
100
73.3
N.A.
N.A.
100
100
93.3
N.A.
N.A.
80
66.6
80
P-Site Similarity:
100
100
20
100
N.A.
100
93.3
N.A.
N.A.
100
100
100
N.A.
N.A.
100
93.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.9
32.7
34.7
Protein Similarity:
N.A.
N.A.
N.A.
48.9
51.9
51.1
P-Site Identity:
N.A.
N.A.
N.A.
80
66.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
93.3
86.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
0
0
0
7
7
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% C
% Asp:
0
7
0
0
0
7
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
60
87
0
0
0
7
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
7
40
0
0
7
7
80
0
0
0
0
0
0
% F
% Gly:
7
0
0
7
0
87
87
0
0
0
0
0
0
0
87
% G
% His:
0
20
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
7
0
0
0
7
7
80
7
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
7
0
0
0
0
0
0
0
0
0
0
0
0
80
0
% L
% Met:
0
7
0
0
0
0
0
0
0
0
0
0
0
7
0
% M
% Asn:
7
0
0
0
0
0
0
0
0
0
0
7
94
0
0
% N
% Pro:
80
7
0
0
0
0
0
0
0
0
0
0
7
14
7
% P
% Gln:
0
0
0
0
94
0
0
0
0
0
0
0
0
0
7
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
7
0
54
0
60
0
87
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
40
7
20
0
0
0
0
0
% T
% Val:
0
0
0
7
0
0
0
0
0
0
20
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
47
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _